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| • | VINTAGE BAUSCH & LOMB MICRO PROJECTOR MICROSCOPE 426359 | ||
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| • | New CU-Boulder study shows diversity decreases chances of parasitic disease | ||
| A new University of Colorado at Boulder study showing that American toads who pal around with gray tree frogs reduce their chances of parasitic infections known to cause limb malformations has strong implications for the benefits of biodiversity on emerging wildlife diseases. (2008-10-22) | |||
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| • | New Anti-cancer Components Of Extra-virgin Olive Oil Revealed | ||
| Good quality extra-virgin olive oil contains health-relevant chemicals, 'phytochemicals', that can trigger cancer cell death. New research sheds more light on the suspected association between olive oil-rich Mediterranean diets and reductions in breast cancer risk. | |||
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| • | Structure Of Virulent Pathogen Revealed | ||
| Like high-profile politicians, pathogenic bacteria dispatch advance teams to make way for their arrival. But these bacterial agents don't just secure a safe passage, as a Secret Service detail might do. Rather they are teams of molecules that bacteria inject into cells they want to colonize, sent to hijack their hosts' biochemistry to serve their master's microbial needs. These molecules -- called virulence factors -- co-opt essential cell functions including the reproduction cycle and cell structure assembly, suppressing the cells' defenses against bacterial invasion and causing disease. | |||
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| • | Effect of ghrelin on gonadotrophin secretion in women during the menstrual cycle | ||
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It has been suggested that ghrelin may affect reproduction in animals by decreasing pituitary LH secretion. The role of ghrelin on LH secretion in women has not been investigated. Our aim was to assess the effect of ghrelin administration on basal and GnRH-induced LH secretion during the menstrual cycle. Normally cycling women (n = 10) received on Day 3 of three consecutive cycles a single bolus i.v. of either ghrelin (1 µg/kg, cycle 1) or GnRH (100 µg, cycle 2) or GnRH plus ghrelin (cycle 3). In cycle 1, ghrelin was also injected in late follicular and mid-luteal phase of the cycle. Saline was injected in a preceding cycle (cycle 1, control). Blood samples were taken before drugs or saline injection (time 0) as well as at –15, 15, 30, 45, 60, 75, 90 and 120 min. Plasma ghrelin levels increased rapidly, peaking at 15 or 30 min (P < 0.001), then decreased steadily, approaching pre-injection levels at 120 min. Serum FSH, LH, estradiol and progesterone levels remained unchanged. The stimulating effect of GnRH on LH and FSH secretion was unaffected by ghrelin injection. In contrast to saline, ghrelin stimulated a significant increase in growth hormone levels. Under these experimental conditions, our results demonstrate for the first time the inability of a bolus of ghrelin to affect basal and GnRH-induced LH and FSH secretion. It is suggested that ghrelin does not play a major physiological role in gonadotrophin secretion in women. |
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| • | Rensselaer and Skidmore, Owings & Merrill LLP Announce Launch of Center for Architecture Science and Ecology | ||
| Nov. 14, 2008: On Friday, November 14, Rensselaer and the renowned architecture firm Skidmore, Owings & Merrill officially launched the Center for Architecture Science and Ecology (CASE). | |||
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| • | Naked Scientists 08.10.19 - Fusion - The Real Solar Power | ||
| Nuclear fusion is the power source inside the Sun - so can we copy the physics of the stars to generate energy here on Earth? This week, we find out how nuclear fusion works, and how to mimic a star on Earth... | |||
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| • | Synthetic Molecules Prevent HIV Virus From Reproducing Within The Body, Study Suggests | ||
| Researchers have identified broad-spectrum aptamers. Aptamers are synthetic molecules that prevent the HIV virus from reproducing. In lab tests, aptamers known as RT5, RT6, RT47 and some variants of those were recently identified to be broad-spectrum, which would allow them to treat many subtypes of HIV-1. Now, researchers are gaining a better understanding of the biochemical characteristics that make aptamers broad-spectrum. | |||
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| • | Fall scenics | ||
| Fall scenics. | |||
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| • | DGS issues report on the geology of Bethany Beach | ||
| The Delaware Geological Survey (DGS) at the University of Delaware released a report that provides new insights into the underground geology and hydrology of southeastern Sussex County, Delaware. | |||
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| • | Field Evaluation of SD Bioline Rapid Malaria Diagnostic Test among Asymptomatic Malaria Infected Children in Port Harcourt, Nigeria | ||
| A rapid immunochromatographic test (SD Bioline malaria P.f/P.v) for the diagnosis of malaria was evaluated against thick blood smears in Port Harcourt, Nigeria, for the purpose of evaluating its efficacy for field work. Two hundred and forty children aged 1-8 years were surveyed in a cross sectional prospective study. For P. falciparum, the SD Bioline was 47% sensitive and 100% specific, with a positive predictive value (PPV) of 100% and a negative predictive value (NPV) of 83.2%. Efficiency of the test was 85.4%. The overall malaria prevalence in this study was 27.5%. P. falciparum accounted for 25.0%, while other species accounted for 2.75%. The cost of the SD Bioline test cassette (US $ 1.98 (230 Naira) per test at the time of study) was quite affordable. We concluded that the sensitivity of SD Bioline is low but with a threshold of 1000 parasites/microlitre among asymptomatic malaria infected children and affordable cost, this RDT (SD Bioline) could serve as a useful epidemiological tool in P. falciparum malaria endemic areas in the developing countries. | |||
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| • | American Alligator | ||
| Dedicated to providing information on the American Alligator. | |||
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| • | MicroSCoPE: December, 2007 Issue | ||
| by Sylvia Currie. ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ In This Issue 1. Collaborate Online Collaborate Online Part 1: Laying the Foundation -December 6 2. Mark Your Calendars *Knowplace Open Weekend: Digital Photo-stories: Enhancing Creativity * Electronic Village Online (EVO) 2008 * If you would like an event to be listed, please contact Sylvia Currie scurrie@sfu.ca. Check the SCoPE calendar for a full list of online events that will be of interest to members. 3. Activity Recap SCoPE seminars are always available for reading and afterthoughts. Access all past seminar discussions 4. PeriSCoPE * Moira Hunter announces that The Call for Participation is open for the 2008 TESOL Electronic Village Online (EVO) event, January 14 - February 24, 2008. * Deirdre Bonnycastle has launched the Active Learning Blog Carnival, bringing in 39 submissions with 24 accepted for the 2nd edition. * The SCoPE Facebook group and member networking is proving to be an interesting way to keep up with members' activities and to discuss our work together. Stop by to write on the wall or start a discussion topic. * Check what SCoPE members are blogging about and subscribe to our SCoPE Bloggers feed. * Have you added your name and location to our Frappr Map? 5. Tips to Improve Your SCoPE Experience 6. About SCoPE Self-register at http://scope.lidc.sfu.ca 7. About MicroSCoPE MicroSCoPE is prepared by Sylvia Currie, Community Coordinator (scurrie@sfu.ca). Please spread the word about SCoPE activities. Distribute this newsletter! |
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| • | Coactivity of sulfide ingredients: a new perspective of the larvicidal activity of garlic essential oil against mosquitoes | ||
| BACKGROUND: The activity of several garlic oil ingredients against Culex pipiens L. larvae was studied. In addition to diallyl sulfide (DS) and diallyl disulfide (DDS), the garlic oils used included one essential oil (EO) and two semi-synthetic garlic essential oils (SSGEO1 and SSGEO2), which resulted from the enrichment of EO with DS and DDS standards respectively. The oils were compared with respect to their toxicity.RESULTS: The chemical composition of the tested oils was evaluated by means of gas chromatography-mass spectrometry. Experimental data from the tested samples revealed high toxicity. In detail, DDS (6.09 mg L-1) was the most active, followed by SSGEO2 (7.05 mg L-1) and EO (8.01 mg L-1), while SSGEO1 and DS were relatively inactive.CONCLUSION: The addition of DDS to EO did not change the toxic effect of the essential oil, whereas the presence of DS in excess produced an enriched essential oil with low toxicity. Furthermore, the antagonistic effect of DS and DDS against the other components of EO was shown by the application of two equations obtained from the literature. Their larvicidal performances were correlated, for the first time, with their detailed chemical composition. Data analysis strongly indicated the toxicity of the other EO sulfur ingredients. Copyright © 2008 Society of Chemical Industry | |||
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| • | 7.344 Antibiotics, Toxins, and Protein Engineering, Spring 2007 (MIT) | ||
| Seminar covering topics of current interest in biology. Includes reading and analysis of research papers and student presentations. Contact Biology Education Office for topics. From the course home page: Course Description The lethal poison Ricin (best known as a weapon of bioterrorism), Diphtheria toxin (the causative agent of a highly contagious bacterial disease), and the widely used antibiotic tetracycline have one thing in common: They specifically target the cell's translational apparatus and disrupt protein synthesis. In this course, we will explore the mechanisms of action of toxins and antibiotics, their roles in everyday medicine, and the emergence and spread of drug resistance. We will also discuss the identification of new drug targets and how we can manipulate the protein synthesis machinery to provide powerful tools for protein engineering and potential new treatments for patients with devastating diseases, such as cystic fibrosis and muscular dystrophy. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive setting. Many instructors of the Advanced Undergraduate Seminars are postdoctoral scientists with a strong interest in teaching. | |||
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| • | LSUHSC's Hill Selected As Fellow Of AAAS | ||
| James M. Hill, PhD, Professor of Ophthalmology, Pharmacology, Microbiology, and Neuroscience at the LSU Health Sciences Center New Orleans School of Medicine, has been awarded the distinction of American Association for the Advancement of Science (AAAS) Fellow. Election as a Fellow is an honor bestowed upon AAAS members by their peers. Dr. | |||
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| • | Unusual Microbial Ropes Grow Slowly In Cave Lake | ||
| Deep inside the Frasassi cave system in Italy and more than 1,600 feet below the Earth's surface, divers found filamentous ropes of microbes growing in the cold water, according to a team of researchers. | |||
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| • | Dried Mushrooms Slow Climate Warming In Northern Forests | ||
| The fight against climate warming has an unexpected ally in mushrooms growing in dry spruce forests covering Alaska, Canada, Scandinavia and other northern regions, a study finds. These findings could influence global climate change predictions and policy. | |||
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| • | New Centre Launched Today To Spearhead UK Research In Synthetic Biology | ||
| Programming biological cells so that they behave like engineering parts is the focus of research at a new UK centre launched today, thanks to an £8 million grant from the Engineering and Physical Sciences Research Council (EPSRC). The new centre will focus on synthetic biology. This is a field in which engineers work with molecular bioscientists to produce biologically-based parts, by modifying DNA. | |||
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| • | Metabolic soft spot identification and compound optimization in early discovery phases using metasite and lc-ms/ms validation | ||
| Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) | |||
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| • | Evaluation of angiogenesis using micro-computed tomography in a xenograft mouse model of lung cancer. | ||
| Authors: Savai R, Langheinrich AC, Schermuly RT, Pullamsetti SS, Dumitrascu R, Traupe H, Rau WS, Seeger W, Grimminger F, Banat GA Quantitative evaluation of lung tumor angiogenesis using immunohistochemical techniques has been limited by difficulties in generating reproducible data. To analyze intrapulmonary tumor angiogenesis, we used high-resolution micro-computed tomography (micro-CT) of lung tumors of mice inoculated with mouse Lewis lung carcinoma (LLC1) or human adenocarcinoma (A549) cell lines. The lung vasculature was filled with the radiopaque silicone rubber, Microfil, through the jugular vein (in vivo application) or pulmonary artery (ex vivo application). In addition, human adenocarcinoma lung tumor-bearing mice treated site-specifically with humanized monoclonal antibody (... | |||
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| • | FIBER OPTIC VIDEO ZOOM INSPECTION MICROSCOPE + CAMERA | ||
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| • | Immunology and evolution of infectious disease | ||
| The book Immunology and evolution of infectious disease was written by Steven A. Frank and is divided into 5 parts. Part 1 covers the background of vertebrate immunity and the benefits of antigenic variation to parasites. Part 2 covers immune recognition and antigenic variants. Part 3 covers the dynamics of a single infection. Part 4 examines variability in hosts and parasites across entire populations and molecular memory of antigens and genetic structure of parasite populations. Part 5 considers different methods to study the evolutionary processes which shape antigenic variation. The book is available to download and is made available on the Web by the National Center for Biotechnology Information (NCBI) from their Bookshelf where a collection of biomedical books have been adapted for the Web. | |||
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| • | Parasites that live inside cells use loophole to thwart immune system | ||
| St. Jude Children's Research Hospital scientists have discovered a mechanism by which intracellular pathogens can shut down one of the body’s key chemical weapons against them: nitric oxide. | |||
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| • | By: unrepentanthippie | ||
| convex: Thanks for asking! Been wanting something like this for several years, but with a computer interface. mr_roboto: Thanks for the recommendation. I went over and bought two, one for me and one for the rugrat (who's 6). |
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| • | Science Update Podcast for 3 October 2008 | ||
| THE SCIENCE OF TREES: Electricity from trees, building a tree from the ground up, a forest of aspirin, and trading rainforest conservation for healthcare. |
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| • | Technonews [Greg Laden's Blog] | ||
Two items of interest for technophiles to read while you take a break from installing and updating and otherwise messing with the new stuff that I know is piled in your living room right now (maybe). Wired top tech breakthroughs of 2008 and a nice pice on the relatoiship between star wars and real technology. Which, of course, is not as important as the relationship between Star Trek and real technology. Read the comments on this post... |
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| • | Mind and Body Cast - Episode 11 - Checking In | ||
| Welcome to Mind and Body Cast, Episode 11, for the 1st week of June, 2007 Visit our website at: http://www.MindandBodyCast.com Email us at: MindandBodyCast@gmail.com
Show Segments: v Intro Ø how to contact us – check out our website at http://www.MindandBodyCast.com Ø email us at MindandBodyCast@gmail.com Ø today’s topic and upcoming segments Ø “In the Reader” health related news end with: Energy Booster Creatine 4/1/7
v Show Topic - Checking In · Aaron update · future shows · http://www.Twitter.com/shayna · http://www.facebook.com/profile.php?id=501040302
v http://www.LifeinTheCrazyLane.com segment – this weeks funny moments · Helping Aaron install a modem · Sidekick ID
v Closing
v Trucker Tom High Definition Video Podcast Promo
Our Pictures at: http://community.webshots.com/user/skibuni30 Our Videos at: http://peppersmama.googlepages.com/myvideos My Blog: http://www.ShaynasBlog.com
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| • | Pope Discusses HIV, TB, Malaria In Annual Peace Address | ||
| Pope Benedict XVI on Thursday during his annual peace address discussed HIV/AIDS, tuberculosis and malaria and said that the three diseases are a common cause of poverty, Agence France-Presse reports (Agence France-Presse, 12/11).Benedict in his address, titled " | |||
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| • | Making flies sick reveals new role for growth factors in immunity | ||
| A Salmonella infection is not a positive experience. However, by infecting the common laboratory fruit fly Drosophila melanogaster with a Salmonella strain known for causing humans intestinal grief, researchers in the School of Life Sciences at Arizona State University have shed light on some key cell regulatory processes - with broad implications for understanding embryonic development, immune function and congenital diseases in humans. (2008-10-27) | |||
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| • | Disruption of colonic barrier function and induction of mediator release by strains of campylobacter jejuni that invade epithelial cells. | ||
| CONCLUSION: These data demonstrate two distinct effects of C. jejuni on colonic epithelial cells and provide an informative model for further investigation of initial host cell responses to C. jejuni. PMID: 19109868 [PubMed - as supplied by publisher] (Source: World Journal of Gastroenterology : WJG) | |||
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By editors@medicalnewstoday.com (MNT Editors) - Copyright 2008, Brightsurf.com - version: v1.5 build A