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| • | Jewel Tweezer for Stereo Microscope Jewelry Collectible | ||
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| • | Fisheries Catch-22: Captive Breeding Aims To Conserve Biodiversity But Plunders Genetic Diversity | ||
| Human impacts on the environment have reduced populations of wild species to dangerously low levels. Nowhere is this more apparent than in worldwide fisheries, where thanks to overfishing and habitat destruction, countless species and populations of fish are on the brink of disappearing forever. To attempt to mitigate the dire situation, captive breeding, the controlled breeding of organisms in protected environments, is regularly initiated. | |||
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| • | New Technique Is Quantum Leap Forward In Understanding Proteins | ||
| Proteins drive critical functioning in the cells of everything from bacteria to humans. But deciphering genomic data to discover just how the thousands upon thousands of proteins in a given organism interact has emerged as one of the most confounding biological challenges of the new century. The new method should enable the development of new antibiotics and other drugs. | |||
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| • | Indicators for metabolic disturbances in anovulatory women with polycystic ovary syndrome diagnosed according to the Rotterdam consensus criteria | ||
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Polycystic ovary syndrome (PCOS) is associated with metabolic abnormalities. It is debated whether all women with PCOS should be screened for metabolic abnormalities as these may vary with PCOS phenotype, age and ethnicity. The aims of this study were to assess the prevalence of metabolic abnormalities in Dutch anovulatory PCOS women and to define criteria for metabolic screening. Anovulatory patients, diagnosed with PCOS according to the Rotterdam consensus criteria, underwent metabolic screening. Through stepwise multivariate analysis patient characteristics associated with metabolic syndrome (MetS) and insulin resistance (IR) were evaluated for their use as selection parameters for metabolic screening. Overall, prevalence of MetS and IR was 15.9% (n = 25) and 14% (n = 22), respectively, in 157 PCOS women (age 29.0 ± 4.8 years, BMI 26.1 ± 6.7 kg/m2). Anovulatory hyperandrogenic women (with or without polycystic ovaries) had more often MetS and IR (with, 20.8 and 19.8%; without, 100 and 40%, respectively) than non-hyperandrogenic PCOS women (0 and 1.8%; P < 0.001). Waist circumference >83.5 cm along with increased free androgen index (FAI) had the most powerful association with the presence of MetS and IR (area under the receiver operating characteristic curve 0.912) and offered a reduction in the necessity of screening for metabolic derailments of about 50%. The hyperandrogenic PCOS phenotypes are highly linked to the presence of MetS and IR in Dutch PCOS women. Waist circumference combined with FAI was identified as an efficient combination test to select those PCOS women who should be screened for the presence of MetS and/or IR. |
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| • | Historic Rensselaer Capital Campaign Reaches Goal Nine Months Ahead of Schedule | ||
| October 1, 2008: Rensselaer announced that it has surpassed the $1.4 billion Renaissance at Rensselaer capital campaign goal. The announcement comes nine months in advance of the campaign's target end date of June 30, 2009, and just days before the opening of the new Experimental Media and Performing Arts Center (EMPAC). | |||
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| • | Naked Scientists 08.07.20 - Discovering Drugs | ||
| Drug Discovery: On this week's Naked Scientists, drug development goes under the microscope as we explore two new ways to find the treatments of tomorrow. We find out why size is important when it comes to chemicals that can kill superbugs, and how soil bacteria hold the chemical clues to the next generation of antibiotics. Plus, how sheets of carbon can be used to reveal single atoms of hydrogen beneath the microscope, how scientists have homed in on the part of the brain linked to obsessive compulsive disorder, and why electronically tagging jellyfish can tell us a sea turtle's secrets. Plus, in Kitchen Science, we make strange and unexpected shapes with bubbles! | |||
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| • | New Strategy For Broad Spectrum Anti-viral Drugs Developed | ||
| Bavituximab, a newly developed anti-viral drug shows promise as a new strategy to fight viral diseases, including potential bioterrorism agents. | |||
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| • | Jeff Taylor Lunar Settlements and Lunar Science lecture. | ||
| Jeff Taylor Lunar Settlements and Lunar Science lecture. | |||
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| • | Provost Rich addresses Faculty Senate on economic situation | ||
| A name change for a college, an update on the effects of the current economic situation on the University of Delaware community and new guidelines for university-wide course breadth requirements topped the items addressed during the Dec. 1 Faculty Senate meeting. | |||
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| • | Effect of Solanum lycocarpum Aqueous Extracts in Helminth Parasites of Conventionally Maintained Laboratory Mice | ||
| This approach intends to add new data on the helminthes parasites of laboratory mice. It has been investigated the anthelmintic activity of Solanum lycocarpum (Solanaceae) extracts against Vampirolepis nana and Aspiculuris tetraptera in mice naturally infected. The extracts were applied for oral saw (intragastric), into the volume of 0.04 mL g-1, with the employing of a dead and bend probe during three consecutive days. The fecal material, collected 24 h after each application, performing a total of four fecal collection, have been softened previously, transferred about to sieve of network of 125 µm and tested under microscope stereoscope, with the objective of behave the identification and counting from the worms eliminated of the second to the fifth day of the experimental. Tukey-Kramer Multiple Comparisons Test was applied to compare the results. According to the analysis of the results it was observed that there were no differences in the % of elimination to the concentration of 10% between TM and UR (from 28.4±3.55 to 29.2±2.92) and statistical differences between TM and C (from 28.4±3.55 to 15.0±1.5) and UR and C (from 29.2±2.92 to 15.0±1.5). To the concentration of was observed that there were differences in the of eliminating between TM and UR (from 30.9±3.43 to 7.7±1.1) and C (from 30.9±3.43 to 15±1.5) related to the experimental which the animal was infecting with Vampirolepis nana. To the concentration of 5% it was observed that there were no differences in the % of elimination between TM and UR (from 4.18±3.33 to 3.70±3.16), TM and C (from 4.18±3.33 to 1.56±3.16) and UR and C (from 3.70±3.16 to 1.56±3.16) related to the experimental which the animal was infected with Aspiculuris tetraptera. It was described that in the chemical analysis of the studied extract there is the presence of glycoalkaloids, a finding that represents a reason for concern since many of these substances are generally toxic and maybe anthelmintic. It was published that medicinal plants which were reported as useful in the treatment of diabetes the S. lycocarpum was the sixth most frequently mentioned. According to the results obtained in the present study, we can speculate that the anthelmintic effect of S. lycocarpum would be related to the action of steroidal alkaloid oligoglycosides as well as the presence of short-chain fatty acids as well as with the concentration of the referred compounds in the extracts. | |||
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| • | High Power Microscopes | ||
| High power or Compound microscopes are used for examining slide preparations of very thin objects, or slices through larger objects, flattened objects or things which are themselves microscopic. | |||
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| • | MicroSCoPE: June 2006 Issue | ||
| by Sylvia Currie. ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ |
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| • | 7.340 Ubiquitination: The Proteasome and Human Disease, Fall 2004 (MIT) | ||
| This seminar provides a deeper understanding of the post-translational mechanisms evolved by eukaryotic cells to target proteins for degradation. Students learn how proteins are recognized and degraded by specific machinery (the proteasome) through their previous tagging with another small protein, ubiquitin. Additional topics include principles of ubiquitin-proteasome function, its control of the most important cellular pathways, and the implication of this system in different human diseases. Finally, speculation on the novel techniques that arose from an increased knowledge of the ubiquitin-proteosome system and current applications in the design of new pharmacological agents to battle disease is also covered. | |||
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| • | New Legionella Course Includes Hands-On Assessment Training | ||
| HC Info's new three-day training course, "Performing High Quality Legionella Assessments," will be held May 19-21 at the Carlsbad Inn Beach Resort in Carlsbad, Calif. The course is for engineers, water treatment specialists, and industrial hygienists that want to provide Legionella assessment services for hospitals, hotels, or industrial facilities; and for public environmental health officials that investigate Legionnaires' disease. | |||
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| • | Hi-tech Vaccine Designed By Students Shows Promise Against Ulcer Causing Bacteria | ||
| Almost half of the world population is infected with bacteria Helicobacter pylori which colonizes stomach, causing gastritis and ulcers and is recognized by WHO as a type I carcinogen. Current antibacterial treatment, implemented after the seminal discovery that H. pylori infection is the underlying cause of ulcers, which brought the discoverers the Nobel Prize in 2005, requires combination of at least three different drugs to eliminate bacteria. | |||
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| • | New Self-training Gene Prediction Program For Fungi Developed | ||
| Researchers have developed a computer program that trains itself to predict genes in the DNA sequences of fungi. The software will be freely available for academic researchers. | |||
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| • | Chimps Study Offers New Insight Into The Origin Of Face Recognition | ||
| Chimpanzees recognize their pals by using some of the same brain regions that switch on when humans register a familiar face, according to a report published online on December 18th in Current Biology, a Cell Press publication. The study - the first to examine brain activity in chimpanzees after they attempt to match fellow chimps' faces - offers new insight into the origin of face recognition in humans, the researchers said. | |||
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| • | Intra-hepatic arterial administration with miriplatin suspended in an oily lymphographic agent inhibits the growth of tumors implanted in rat livers by inducing platinum-dna adducts to form and massive apoptosis | ||
| Conclusion Miriplatin appears to be a suitable chemotherapeutic agent for transarterial chemoembolization. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00280-008-0895-3Authors Mitsuharu Hanada, Dainippon Sumitomo Pharma Co., Ltd Pharmacology Research Laboratories 3-1-98, Kasugadenaka, Konohana-ku Osaka 554-0022 JapanAkemi Baba, Dainippon Sumitomo Pharma Co., Ltd Pharmacology Research Laboratories 3-1-98, Kasugadenaka, Konohana-ku Osaka 554-0022 JapanYasuyuki Tsutsumishita, Dainippon Sumitomo Pharma Co., Ltd Pharmacology Research Laboratories 3-1-98, Kasugadenaka, Konohana-ku Osaka 554-0022 JapanToshihiro Noguchi, Dainippon Sumitomo Pharma Co., Ltd Pharmacology Research Laboratories 3-1-98, Kasugadenaka, Konohana-ku Osaka 554-0022 JapanTakashi Yamaok... | |||
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| • | Incident hypercholesterolemia in relation to changes in vigorous physical activity. | ||
| Page: 74DOI: 10.1249/MSS.0b013e3181831417Authors: WILLIAMS, PAUL T. (Source: Medicine & Science in Sports & Exercise) | |||
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| • | 40-400x POLARIZING PETROGRAPHIC GEOLOGY ROCK MICROSCOPE | ||
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| • | New clue to machinery of autoimmune disease | ||
| St. Jude researchers have discovered an intriguing insight into how T cells, the immune system’s master regulatory cells, wage war on the body’s own tissues in such autoimmune disorders as multiple sclerosis, type 1 diabetes and rheumatoid arthritis. | |||
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| • | Science Update Podcast for 26 June 2008 | ||
| COMPUTERS & BIOLOGY: Both bacteria and beetles promise to speed up computing, a computer game that could lead to a cure for deadly diseases, and more. |
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| • | Eric Holder's NFL steroid-scandal involvement [Dr. Joan Bushwell's Chimpanzee Refuge] | ||
Barack Obama's pick for the top cop in the United States has an interesting past, having been enlisted by the NFL to combat the onslaught of congressional hearings and other forms of bad publicity last year. The attorney-general-to-be and deputy attorney general under Bill Clinton was a partner in Covington & Burling, a D.C. law firm that has long extended services to the NFL. Since 2001, Holder has been involved in the investigation of the dog-fighting charges against Michael Vick, the implementation of the rule requiring team owners to interview minority candidates for coaching vacancies, and the league's personal-conduct crackdown, some elements of which have reached silly proportions. Holder and his supporting cast did not get what they hoped for last year, and law-enforcement officials have called his efforts a mere attempt to keep the league from suffering further black eyes rather than an earnest attempt to curb a performance-enhancing drug problem: Read the rest of this post... | Read the comments on this post... |
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| • | Mind and Body Cast Promo | ||
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| • | Crippling, Often Fatal Forms Of Malaria Could Be Diagnosed From Biomarkers In Blood | ||
| Canadian researchers describe double malaria breakthrough in New Orleans Canadian researchers have identified protein biomarkers that shed new light on the development of two severe and debilitating forms of malaria. | |||
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| • | The story of human cytomegalovirus and cancer: increasing evidence and open questions. | ||
| Authors: Michaelis M, Doerr HW, Cinatl J Although human cytomegalovirus (HCMV) is generally not regarded to be an oncogenic virus, HCMV infection has been implicated in malignant diseases from different cancer entities. On the basis of our experimental findings, we developed the concept of "oncomodulation" to better explain the role of HCMV in cancer. Oncomodulation means that HCMV infects tumor cells and increases their malignancy. By this concept, HCMV was proposed to be a therapeutic target in a fraction of cancer patients. However, the clinical relevance of HCMV-induced oncomodulation remains to be clarified. One central question that has to be definitively answered is if HCMV establishes persistent virus replication in tumor cells or not. In our eyes, recent clinical findings from... | |||
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