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| • | Outsourcing|Freelance projects|Freelancer | ||
| Net4manpower.com home of the best web master projects. Whether you are a webmaster seeking to avail the service of a freelancer or whether you are a freelance programmer in search of a competitive webmaster project or a permanent job, we are here to help you with your outsource project needs. we offers full time/part time home based jobs for web designer,multimedia,flash,animation designers,proof readers, writers,etc.... | |||
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| • | Humans Prompted New Paths For Parasites | ||
| Scientists are tracking how the dissemination of the parasite Trichinella spiralis throughout Europe, North Africa and the Americas was facilitated by human travel and the transportation of animals. | |||
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| • | How DNA Is Unwound So That Its Code Can Be Read | ||
| Researchers have figured out how a macromolecular machine is able to unwind the long and twisted tangles of DNA within a cell's nucleus so that genetic information can be "read" and used to direct the synthesis of proteins, which have many specific functions in the body. | |||
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| • | Variants in the ACVR1 gene are associated with AMH levels in women with polycystic ovary syndrome | ||
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Polycystic ovaries display an increased number of pre-antral and antral follicles compared with normal ovaries, suggesting that early and late follicle development are disturbed. The pathophysiology of this process is poorly understood. Since the transforming growth factor β family members, anti-Müllerian hormone (AMH) and bone morphogenetic proteins (BMPs), inhibit FSH sensitivity, their signalling may contribute to the aberrant follicle development in these women. Here, we investigated the role of ALK2, a type I receptor for AMH/BMP signalling, in PCOS using a genetic approach. Seven single nucleotide polymorphisms in the ACVR1 gene, encoding ALK2, were genotyped in 359 PCOS patients and 30 normo-ovulatory and 3543 population-based control women, and haplotypes were determined. Subsequently, the association of ACVR1 variants with ovarian parameters and hormone levels was investigated. The polymorphisms rs1220134, rs10497189 and rs2033962 and their corresponding haplotypes did not show different frequencies from controls, but were associated with AMH levels in PCOS women (P = 0.001, P = 0.002 and P = 0.007, respectively). Adjustment for follicle number revealed that the association with AMH levels was, in part, independent from follicle number, suggesting that variants in ACVR1 also influence AMH production per follicle. Genetic variation within ACVR1 is associated with AMH levels and follicle number in PCOS women, suggesting that ALK2 signalling contributes to the disturbed folliculogenesis in PCOS patients. |
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| • | Rensselaer Announces New Head of Institute Advancement | ||
| September 19, 2008: Robert Schlesinger, an experienced professional in university development and alumni relations, will join Rensselaer on October 1 as the vice president for institute advancement. | |||
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| • | Naked Scientists 08.06.01 - Questions and Answers | ||
| Footballs in space, mind-controlled machines and long-lasting bubbles join your questions on this week's Naked Scientists Question and Answer show. We discover the feminine side of prostate cancer and the robot that can walk up walls, and also hear how a computer has designed the next generation of mosquito repellents. Plus, we revisit the Phoenix mission on Mars, and also find out how surfing the internet can contribute more carbon to climate change than surfing the skies in an aeroplane! Plus, in Kitchen Science, Dave demonstrates a psychedelic effect with some milk. | |||
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| • | 1918 Spanish Flu Records Could Hold The Key To Solving Future Pandemics | ||
| Ninety years after Australian scientists began their race to stop the spread of Spanish flu in Australia, University of Melbourne researchers are hoping records from the 1918 epidemic may hold the key to preventing future deadly pandemic outbreaks. | |||
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| • | New: Tony Bretscher and Scott Emr, Professors of Molecular Biology and Genetics. | ||
| L-R: Tony Bretscher, Professor of Cell Biology and Associate Director of the Weill Institute for Cell and Molecular Biology, and Scott Emr, Professor of Molecular Biology and Genetics, and Director of the Weill Institute for Cell and Molecular Biology. | |||
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| • | NIH awards $3 million grant to study movement disorders | ||
| A multidisciplinary research team from the University of Delaware departments of Mechanical Engineering and Physical Therapy has been awarded a five-year, $3 million grant from the National Institutes of Health (NIH) to continue a study on the treatment of movement disorders. The grant was awarded under NIH's Bioengineering Research Partnerships (BRP) program. | |||
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| • | Antimalarial Activities of Some Selected Traditional Herbs from South Eastern Nigeria Against Plasmodium Species | ||
| A study of three plants traditionally used in the treatment of malaria in the Southeastern part of Nigeria was investigated to determine their efficacies as antimalarial compounds. The three herbs were collected through a traditional herbalist who uses them in his practice. Ethanolic extracts from the roots of Enyim ocha (Salacia nitida), Ovoro ilu (Nauclea latifolia) and stem bark of Erumeru (Enantia chlorantha Oliv.) were assessed for antimalarial activity against chloroquine sensitive Plasmodium berghei in mice using the 4 day suppressive test procedure. The extracts had intrinsic antimalarial properties that were dose dependent. The comparison analysis indicated that 250 mg kg-1 body weight of the root of S. nitida produced 71.15% suppression of parasitaemia and the 500 mg kg-1 body weight of the stem bark of E. chlorantha, roots of S. nitida, N. latifolia and the three herbs combined, produced 75.23, 73.28, 71.15 and 77.46%, respectively, compared with chloroquine with 71.15% suppression. The results were significant at p< 0.05 when compared to a placebo and support the traditional use of these plants for the treatment of malaria. | |||
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| • | Clinical Microscopes | ||
| Clinical Microscopes is your source of Medical Microscopes for Physicians, Doctors and other Medical Professionals. | |||
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| • | Special announcement: KnowTIPS Online Conference begins today! | ||
| by Sylvia Currie. The 2nd Annual KnowTIPS Online Conference begins today! KnowTIPS is an example of what energetic and committed individuals can achieve as a group. |
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| • | Differential toxicity of Bacillus thuringiensis strains and their crystal toxins against high-altitude Himalayan populations of diamondback moth, Plutella xylostella L. | ||
| BACKGROUND: Diamondback moth, Plutella xylostella (L.), is a major insect pest of crucifers in the biodiversity-rich north-western Indian Himalayan hills. The present investigation was aimed at determining the susceptibility pattern of P. xylostella populations collected from different locations of this region to autochthonous and standard Bacillus thuringiensis strains.RESULTS: Among the reference as well as indigenous B. thuringiensis strains tested, sub spp. kurstaki HD-1, kurstaki HD-73, galleriae HD-8, local galleriae/colmeri strain BtOa1 and some of their Cry1 class toxins were found to be highly toxic. Surprisingly, the sub sp. tolworthi HD-125, local tolworthi strain BtHa1 and Cry9 class toxins were found to be non-toxic. Midgut homogenate from fourth-instar larvae was found to activate 130 kDa protoxin from the local tolworthi strain BtHa1 into 68 kDa toxin, but failed to exert any larval mortality, probably owing to lack of receptor binding.CONCLUSION: The present study provides valuable baseline susceptibility data for the deployment of B. thuringiensis-based control methods, as well as for future monitoring of development of resistance in P. xylostella to B. thuringiensis in this ecologically sensitive region. Copyright © 2008 Society of Chemical Industry | |||
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| • | 7.342 Reading the Blueprint of Life: Transcription, Stem Cells and Differentiation, Fall 2006 (MIT) | ||
| Seminar covering topics of current interest in biology. Includes reading and analysis of research papers and student presentations. Contact Biology Education Office for topics. Description from course home page: In this course, we will address how transcriptional regulators both prohibit and drive differentiation during the course of development. How does a stem cell know when to remain a stem cell and when to become a specific cell type? Are there global differences in the way the genome is read in multipotent and terminally differentiated cells? We will explore how stem cell pluripotency is preserved, how master regulators of cell-fate decisions execute developmental programs, and how chromatin regulators control undifferentiated versus differentiated states. Additionally, we will discuss how aberrant regulation of transcriptional regulators produces disorders such as developmental defects and cancer. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive setting. Many instructors of the Advanced Undergraduate Seminars are postdoctoral scientists with a strong interest in teaching. | |||
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| • | Food Safety Tips For Thanksgiving - Wisconsin Department Of Health Services | ||
| MADISON-State health officials are reminding everyone that following basic food safety tips can greatly reduce the chances of a foodborne illness becoming part of your holiday memories. The four basic rules of food safety are: - Clean - Wash hands and food-contact (cutting boards) surfaces often. Bacteria can spread throughout the kitchen and get onto cutting boards, knives, sponges, and counter tops. | |||
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| • | Antibiotics Can Cause Pervasive, Persistent Changes To Microbiota In Human Gut | ||
| Using a novel technique developed at the Marine Biological Laboratory to identify different types of bacteria, scientists have completed the most precise survey to date of how microbial communities in the human gut respond to antibiotic treatment. | |||
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| • | How Plants Fine Tune Their Natural Chemical Defenses | ||
| Even closely related plants produce their own natural chemical cocktails, each set uniquely adapted to the individual plant's specific habitat. Comparing antifungals produced by tobacco and henbane, researchers have discovered that only a few mutations in a key enzyme are enough to shift the whole output to an entirely new product mixture. | |||
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| • | New Findings May Hold The Key To Where The Gene Activity Of Youth Goes | ||
| New evidence may explain why it is that we lose not only our youthful looks, but also our youthful pattern of gene activity with age. A report in the November 26th issue of the journal Cell, a Cell Press publication, reveals that a protein perhaps best known for its role in the life-extending benefits of a low-calorie diet also maintains the stability of the mammalian genome - the complete set of genetic instructions "written" in DNA. | |||
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| • | Effects of indium segregation on optical properties of nitrogen-doped inas/gaas quantum dots | ||
| Tomoya Inoue, Masataka Mamizuka, Hiroshi Mizuno, Osamu Kojima, Takashi Kita et al. The emission wavelength of InAs quantum dots (QDs) capped by GaAs is found to be systematically controlled by doping nitrogen on the QDs surface with a thin spacer layer in between QDs and the nitrogen-doped layer. Cross-sectional transmission electron microscope images of the nitrogen-doped QD indi ... [J. Appl. Phys. 104, 103532 (2008)] published Mon Nov 24, 2008. (Source: Journal of Applied Physics) | |||
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| • | Genetic data of 15 str loci in chinese yunnan han population | ||
| Abstract: The allelic distribution of 15 short tandem repeats (STRs) loci (D8S1179, D21S11, D7S820, CSF1PO, D3S1358, TH01, D13S317, D16S539, D2S1338, D19S433, vWA, TPOX, D18S51, D5S818 and FGA) were tested in 497 unrelated Yunnan Han individuals by the AmpFl STR® Identifiler™ kit. No deviation from Hardy–Weinberg equilibrium was observed except D7S820 locus treated by Bonferroni correction. Genetic parameters of forensic interests were calculated and the genetic differences between Yunnan Han and other eight populations were analyzed. (Source: Forensic Science International: Genetics) | |||
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| • | 40x-400x POLARIZING TRINOCULAR PETROGRAPHIC MICROSCOPE | ||
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| • | (clone of)St. Jude study reveals a new function for an old enzyme in fatal childhood disease (news release) | ||
| A ubiquitous housekeeping enzyme has been found to play a major role in keeping the bone marrow environment healthy so it can nurture hematopoietic stem cells. | |||
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| • | Science Update Podcast for 23 May 2008 | ||
| MEDICINE & TECHNOLOGY: CSI in the hospital, remote medicine with cellular phones, a better gas mask, the influence of cancer cells, and an upsurge in gestational diabetes. |
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| • | Putting Baby Mojo to the Test [Uncertain Principles] | ||
It has been observed that my New York Football Giants are undefeated this year in games where SteelyKid was present for the game, and happy. The one game they've lost, an inexcusable thrashing by the otherwise hapless Browns, was a night game, and Kate took her upstairs for a final feeding before kickoff, and put her to bed immediately afterwards, so she wasn't on hand for the ugliness. We put this to the test today, thanks to a delay on Interstate 88 near Unadilla. We should've been home right around kickoff, but an accident closed the highway, and we sat parked on the road for a good 45 minutes, and between that and the icy slush, we didn't get home until halftime. The correlation remains intact, however. Read the rest of this post... | Read the comments on this post... |
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| • | Describing West Nile's North American Spread | ||
| The rapid spread of West Nile virus in North America over the past decade is likely to have long-lasting ecological consequences throughout the continent, according to an article in the November issue of BioScience. The mosquito-borne virus, which was little known before its emergence in New York in 1999, has since been found in all 48 contiguous states. | |||
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| • | Adult form of pompe disease. | ||
| We report the case of a 24-year-old student admitted to the Department of Pulmonary Diseases because of severe respiratory insufficiency. Clinical symptoms such as dyspnea, muscular weakness and increased daytime sleepiness had been progressing for 2 years. Clinical examination and increased blood levels of CK suggested muscle pathology. Histopathological analysis of muscle biopsy, performed under electron microscope, confirmed the presence of vacuoles containing glycogen. Specific enzymatic activity of alpha-glucosidase was analyzed confirming Pompe disease. The only effective method to treat respiratory insufficiency was bi-level positive pressure ventilation. Respiratory rehabilitation was instituted and is still being continued by the patient at home. A high-protein, low-sugar diet was... | |||
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By editors@medicalnewstoday.com (MNT Editors) - Copyright 2008, Brightsurf.com - version: v1.5 build A